麻烦各位大侠帮忙翻译一下

    （1) 1 months treatment bullous class day blister boils regimen dosage or the change;
(2) in serious difficult to control the local or systemic acute and chronic infection, may influence test drug use or the clinical evaluation;
(3) with severe heart, lung, and liver (such as transaminase just above the average 1。
    5 times or more), cap and other important kidney disease patients;
(4) pregnant women, lactation women or recent have fertility planners;
(5) a malignant tumor of history;
(6) to the trial drug allergy or have contraindication license;
(7) have influence of clinical evaluation of other skin disease;
(8) have the researchers think unfit for test of the other situations。
    
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